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1 April 2009HORMONE REPLACEMENT IN CASE OF OSTEOPOROSIS: HORMONES FOR RETARDING BONE LOSS

It is now the commonly shared view of many experts that oestrogen hormones are highly effective for the prevention of osteoporosis, reducing bone resorption and retarding postmenopausal bone loss. Doctors are finding 60 per cent fewer fractures of the hip and wrist among older women who started low-dose oestrogen therapy within a few years of menopause. Studies also suggest that oestrogen reduces the rate of vertebral fractures. Even when therapy is begun six years after menopause, oestrogen stems further decrease of bone mass – although it does not restore it to pre-menopausal levels. But there is no convincing evidence yet that osteoporosis will be prevented if oestrogen therapy is started in very elderly women.

Replacement oestrogen can give relief of hot flashes, drenching perspiration, vaginal dryness, and have a major protective effect against cardiovascular disease in postmenopausal women — an important consideration in this age group.

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